Dr Ronan Lordan

Available to discuss new collaborations, science outreach or speaking opportunities. Feel free to make contact via email or twitter.



Institute for Translational Medicine and Therapeutics

Perelman School of Medicine, University of Pennsylvania



Dr Ronan Lordan

Available to discuss new collaborations, science outreach or speaking opportunities. Feel free to make contact via email or twitter.


Contact

Dr Ronan Lordan

Available to discuss new collaborations, science outreach or speaking opportunities. Feel free to make contact via email or twitter.



Institute for Translational Medicine and Therapeutics

Perelman School of Medicine, University of Pennsylvania




About


Dr Ronan Lordan is an Irish researcher in Philadelphia working in the area of circadian biology, aging, metabolism, and nutrition at the FitzGerald Laboratory at the Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania.

His current research interests include:
(a) Circadian biology, metabolism, and ageing.
(b) Investigating the role of exercise in aging phenotypes in Bmal1  knockout mice.
(c) Discerning the role of lipid mediators such as eicosanoids and platelet-activating factors in atherosclerosis and inflammatory diseases.
(d)
Exploring the role of diet and lifestyle for the prevention of cardiovascular diseases via identification of pharmacologically active dietary polar lipids.
(e)
Regulation, safety, and efficacy of functional foods and nutraceuticals.

Check out the webpage for research, science communication and how to make contact.

Also check out the FitzGerald Lab webpage for more info and exciting science: https://www.med.upenn.edu/fitzgeraldlab/

Publications


Digital health and mobile health: a bibliometric analysis of the 100 most cited papers and their contributing authors


Awk Yeung, O. Litvinova, N. Bragazzi, Yousef Khader, Md. Mostafizur Rahman, Zafar Said, Robert S. H. Istepanian, Anastasios Koulaouzidis, A. Aremu, James M. Flanagan, N. Rabiee, Sheikh Mohammed Shariful Islam, Devesh Tewari, G. Venkatachalam, G. Orlando, J. Niebauer, A. Georgakilas, M. Saeb, Dalibor Hrg, Yufei Yuan, M. Imran, H. Cheng, Eliana B. Souto, H. P. Devkota, M. Leone, J. G. Manjunatha, Nikolay T. Tzvetkov, Maima Matin, Olga Adamska, S. Völkl-Kernstock, Fabian Peter Hammerle, Farhan Bin Matin, B. N. Siddiquea, Dongdong Wang, Jivko Stoyanov, J. O. Horbańczuk, Magdalena Koszarska, Emil D. Parvanov, Iga Bartel, A. Jóźwik, Natalia Ksepka, Bogumila Zima-Kulisiewicz, Björn W. Schuller, Gaurav Pandey, David W. Bates, T. Y. Wong, Benjamin S. Glicksberg, Maciej Banach, C. Tomasik, Seifedien Kadry, Stephen T C Wong, R. Lordan, Faisal A. Nawaz, Rajeev K. Singla, A. MohanaSundaram, Himel Mondal, Ayesha Juhi, Shaikat Mondal, M. Cenanovic, Aleksandra Zielińska, C. Tsagkaris, Ronita De, Siva Sai Chandragiri, R. Damaševičius, Mugisha Nsengiyumva, A. Stolarczyk, Okyaz Eminaga, M. Cascella, H. Willschke, Atanas G. Atanasov

Exploration of Digital Health Technologies, 2024


Disruption of the PGE2 synthesis / response pathway restrains atherogenesis in programmed cell death-1 (Pd-1) deficient hyperlipidemic mice


E. Ricciotti, S. Tang, Antonijo Mrcela, U. S. Das, R. Lordan, Robin Joshi, Soumita Ghosh, Justin Aoyama, Ryan McConnell, Jianing Yang, Gregory R Grant, Garret A. FitzGerald

bioRxiv, 2024


Polar lipids modify Alzheimer’s Disease pathology by reducing astrocyte pro-inflammatory signaling through platelet-activating factor receptor (PTAFR) modulation


Sakshi Hans, Janelle E Stanton, Ann Katrin Sauer, Katie Shiels, S. K. Saha, R. Lordan, A. Tsoupras, I. Zabetakis, A. Grabrucker

Lipids in Health and Disease, 2024


Bioactive lipids derived from red wine, beers, and their dealcoholized variants inhibit platelet-activating factor (PAF) induced platelet activation in vitro


Sakshi Hans, Rajendran Harishkumar, Katie Shiels, Sushanta Kumar Saha, Hannah Toohey, Lucy Cunneen, Aleksander Nalewajka, Ioannis Zabetakis, R. Lordan

Food Bioscience, 2024


Milk Polar lipids: Untapped Potential for Pharmaceuticals and Nutraceuticals


Aditi Pawar, I. Zabetakis, Tanvi Gavankar, R. Lordan

PharmaNutrition, 2023


View all

Projects




Circadian Regulation of Metabolism and Aging


2020 - Present: This project aims to understand the role of circadian misalignment and its contribution to metabolic diseases and aging, with a focus on Bmal1.




Lipid Mediators of Inflammation


2016 - Present: Platelet-activating factor (PAF), prostaglandins, and leukotrienes play a pivotal role in inflammatory signaling. We are interested in the development of novel therapeutic agents targeting these inflammatory mediators.




COVID-19 Research and Review Consortium


2020 - 2021: COVID-19 Review Consortium at UPenn. Our aim is to distill the existing COVID-19 literature into reviews that document the most reliable research to date in the areas of pathogenesis, therapeutics, prophylactics, and diagnostics.




2018 - 2021: Heart Healthy Salmon Nutraceuticals


The aim of this project was to assess the antioxidant properties and elucidate the structures of antithrombotic polar lipids from farmed Atlantic salmon using C30RP-UHPLC-HRAM-MS/MS for the development of novel nutraceuticals.




COVID-19 Supplements Research


Research regarding COVID-19 supplements and nutrition

Contact


Dr Ronan Lordan

Available to discuss new collaborations, science outreach or speaking opportunities. Feel free to make contact via email or twitter.



Institute for Translational Medicine and Therapeutics

Perelman School of Medicine, University of Pennsylvania


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