Dr Ronan Lordan

Available to discuss new collaborations, science communication, outreach or speaking opportunities. Contact via email.



Institute for Translational Medicine and Therapeutics

Perelman School of Medicine, University of Pennsylvania



Circadian Regulation of Metabolism and Aging


This is an ongoing project at the FitzGerald lab, which aims to examine the following topics:
 
1. Exercise training, exercise tolerance, ageing and circadian biology of skeletal muscle.

2. Sexual dimorphism in the response to chronic circadian misalignment.

Project Updates 2022-2024:


Review: Intersection of sex and circadian biology - September 2025

A review article in the journal Current Opinion in Physiology regarding updates in sexually dimorphic research in circadian biology

Invited Conference Talk: Pennsylvania Muscle Institute, University of Pennsylvania, Philadelphia, PA, USA - July 2024

Talk title: Endurance exercise training partially rescues aged metabolic phenotypes and improves health span in mice lacking a functional circadian clock.

Presented at the Spring 2025 Pennsylvania Muscle Institute - From Molecules to Movement: Cytoskeletal Insights into Muscle Function and Neuronal Health. 
PMI Poster Session 2025
PMI Poster Session 2025
Presenting at PMI 2025
Presenting at PMI 2025
PMI Symposium 2025
PMI Symposium 2025


Journal Club Paper: Sex and the clock: Time to consider sexually dimorphic rhythms in circadian research - March 2025

A Journal Club Article in the Journal of Biological Rhythms regarding sexually dimorphic rhythms in sleep architecture.


Preprint: Brown adipose tissue thermogenesis rhythms are driven by the SCN independent of adipocyte clocks - October 2024

Bioxiv Preprint led by Dr Georgios Paschos in the FitzGerald Lab.


Journal Club Paper: The dark side of shift work: circadian misalignment of skeletal muscle - September 2023

A Journal Club Article in Nature Reviews Endocrinology regarding shift work and muscle metabolism.


Research Seminar: Royal College of Surgeons, Dublin, Ireland, (RCSI)  - July 2024

Talk title: The crucial links between circadian rhythms, metabolism, exercise, and aging

Hosted by Dr Cristina Ruedell Reschke & Dr Annie Curtis, School of Pharmacy and Biomolecular Sciences, RCSI, Dublin, Ireland.
Networking with Dr Cristina Ruedell Reschke & team.
Networking with Dr Cristina Ruedell Reschke & team.
Presenting at the Royal College of Surgeons, Dublin, Ireland.
Presenting at the Royal College of Surgeons, Dublin, Ireland.


Invited Seminar: University of Limerick, Ireland, Department of Biological Sciences - July 2024

Talk title: Biology around the clock: Circadian rhythms in metabolism, exercise, and aging

Hosted by Di Eibhlis O' Conner the Department of Biological Sciences, University of Limerick, Ireland. 


Conference: International Biochemistry of Exercise Conference, University of Limerick, Ireland - IBEC, July 2024 

Poster: Endurance exercise training rescues metabolic phenotypes in mice lacking a function circadian clock

Invited Conference Talk: CSI Research Retreat, University of Pennsylvania, Philadelphia, PA, USA - October, 2023.

Talk title: The timing of Bmal1 deletion differentially impacts skeletal muscle morphology, function, and features of aging.

Presented at the Chronobiology and Sleep Institute (CSI) Research Retreat, Rubenstein Auditorium, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. 
Presenting at the CSI 2023 Retreat
Presenting at the CSI 2023 Retreat
Q&A session at the CSI retreat
Q&A session at the CSI retreat


Conference: Advances in Skeletal Muscle Conference, University of Florida Myology Institute, Gainesville, FL, USA - March, 2023.

Winner of the Aurora Scientific Outstanding Poster Award for the project titled: The timing of Bmal1 deletion differentially impacts skeletal muscle morphology, function, and features of aging
Aurora Scientific Outstanding Poster Award
University of Florida, Gainesville, Florida


Paper: Sexual dimorphism in the response to chronic circadian misalignment on a high-fat diet - Published in Science Translational Medicine - May 2023

Study led by Dr Sean Anderson, FitzGerald Lab, Penn.
Sexual dimorphism in the response to chronic circadian misalignment on a high-fat diet


Review: The circadian biology of heart failure - January 2023

A review led by Dr Nadim El Jamal, FitzGerald Lab, UPenn.


Research Paper: Circadian disruption in lung fibroblasts enhances NF-kB activity to exacerbate neutrophil recruitment - January 2023

Study led by Dr Shannon Cox from the Curtis Lab, in RCSI, Dublin, Ireland.

Perelman School of Medicine Postdoctoral Research Seminar April 2022

Poster presentation April 2022
Title: Timing of
Bmal1 deletion differentially impacts skeletal muscle morphology and function
Dr Ronan Lordan poster presentation at the University of Pennsylvania, Perelman School of Medicine Postdoc Symposium. April 2022.


Invited Seminar: University of Limerick, Department of Biological Sciences - July 2022

Title: The complex role of Bmal1 and the circadian clock in metabolism and aging
Hosted by Dr Ioannis Zabetakis, Bernal Institute, University of Limerick, Ireland. 
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