Journal article
2020
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Institute for Translational Medicine and Therapeutics
Perelman School of Medicine, University of Pennsylvania
APA
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Lordan, R., Zabetakis, I., & Tsoupras, A. (2020). Inflammation and Chronic Diseases: The Polar Lipid Link.
Chicago/Turabian
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Lordan, R., I. Zabetakis, and A. Tsoupras. “Inflammation and Chronic Diseases: The Polar Lipid Link” (2020).
MLA
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Lordan, R., et al. Inflammation and Chronic Diseases: The Polar Lipid Link. 2020.
BibTeX Click to copy
@article{r2020a,
title = {Inflammation and Chronic Diseases: The Polar Lipid Link},
year = {2020},
author = {Lordan, R. and Zabetakis, I. and Tsoupras, A.}
}
Cardiovascular diseases (CVD) are the leading cause of death globally. The focus of scientists and practitioners for decades has been on cholesterol levels and pharmacological ways to control it. Over the past few years a new school of thought has emerged: it's not cholesterol but inflammation that causes chronic non-communicable diseases (NCD). Therefore, the key to reducing the incidence of chronic diseases is to control the activities of various inflammatory mediators such as platelet-activating factor (PAF) via diet, exercise, and healthy lifestyle choices. One proposal has been that polar lipids present in foods can play a key role via their antithrombotic and anti-inflammatory bioactivities. In this paper, we present our latest views on PAF and how it is related to CVD and we discuss the role of diet and polar lipids against inflammation PAF-induced inflammation.