Dr Ronan Lordan

Available to discuss new collaborations, science outreach or speaking opportunities. Feel free to make contact via email or twitter.



Institute for Translational Medicine and Therapeutics

Perelman School of Medicine, University of Pennsylvania



Inflammation and Chronic Diseases: The Polar Lipid Link


Journal article


R. Lordan, I. Zabetakis, A. Tsoupras
2020

Semantic Scholar DOI
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Cite

APA   Click to copy
Lordan, R., Zabetakis, I., & Tsoupras, A. (2020). Inflammation and Chronic Diseases: The Polar Lipid Link.


Chicago/Turabian   Click to copy
Lordan, R., I. Zabetakis, and A. Tsoupras. “Inflammation and Chronic Diseases: The Polar Lipid Link” (2020).


MLA   Click to copy
Lordan, R., et al. Inflammation and Chronic Diseases: The Polar Lipid Link. 2020.


BibTeX   Click to copy

@article{r2020a,
  title = {Inflammation and Chronic Diseases: The Polar Lipid Link},
  year = {2020},
  author = {Lordan, R. and Zabetakis, I. and Tsoupras, A.}
}

Abstract

Cardiovascular diseases (CVD) are the leading cause of death globally. The focus of scientists and practitioners for decades has been on cholesterol levels and pharmacological ways to control it. Over the past few years a new school of thought has emerged: it's not cholesterol but inflammation that causes chronic non-communicable diseases (NCD). Therefore, the key to reducing the incidence of chronic diseases is to control the activities of various inflammatory mediators such as platelet-activating factor (PAF) via diet, exercise, and healthy lifestyle choices. One proposal has been that polar lipids present in foods can play a key role via their antithrombotic and anti-inflammatory bioactivities. In this paper, we present our latest views on PAF and how it is related to CVD and we discuss the role of diet and polar lipids against inflammation PAF-induced inflammation.


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